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Glucagon-like peptide-1 (GLP-1) treatments have demonstrated remarkable effectiveness in addressing major public health issues, including diabetes and obesity.

Accelerate and derisk your GLP-1 drug development programs with Aptar Pharma’s reliable packaging solutions, including rigid needle shields (RNS), pre-filled syringe (PFS) and cartridge plungers. Our advanced parenteral closure solutions help optimize and secure your fill-finish operations.

Accelerate and Derisk the Development of Your GLP-1 Drugs for Diabetes and Obesity Treatments

 

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Platform of pre-filled system components

Glucagon-like peptide-1 (GLP-1) based self-injection drugs for type 2 diabetes and obesity often rely on autoinjectors or pen injector systems to ensure their safe and effective administration by patients.

Aptar Pharma offers a range of high-quality components to support your GLP-1 product development needs:

  • Pre-filled syringe (PFS) plungers
  • Rigid needle shields (RNS)
  • Cartridge plungers for pen-injectors

Take your development from formulation to patient with Aptar Pharma’s drug development services, innovative solutions and patient services that support the success of your self-injected GLP-1 drug products for diabetes and obesity.

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Ensure your long-term security of supply of GLP-1 injectable components

With a growing market for diabetes and obesity treatments, securing your long-term security of supply of GLP-1 self-injection components is essential. We continue to expand our injectable component manufacturing capabilities, leveraging robotization and clean room manufacturing capacity to ensure you receive ever-increasing quality worldwide.

With a new factory in Europe, new manufacturing lines in the US and worldwide upgrade plans, we are investing in capabilities to support your drug developments needs and transform your expectations of what an injectable partner should be.

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Accelerate and derisk your GLP-1 drug and delivery device development

When developing glucagon-like peptide-1 (GLP-1) drugs, such as for diabetes or obesity, the compatibility of the formulation with the primary container is a major concern that could potentially delay regulatory approval.

Leverage Aptar Pharma’s pure rubber component formulation, market proven component designs and clean room manufacturing capabilities to promote drug to component compatibility. For your most sensitive drug development programs, choose PremiumCoat® ETFE film-coated plungers to further reduce the risks related to extractables, and leachables.

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Facilitate your choice of primary packaging

Selecting the right primary packaging partner is essential to derisk your regulatory review and reduce time-to-market. World-leading glass-manufacturing and pharmaceutical companies have already validated our pre-filled syringe component solutions and are partnering with us to develop self-injection devices for glucagon-like peptide-1 (GLP-1) and a wide range of other applications.

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Support your brand image and differentiate your GLP-1 drug

As GLP-1 drugs are getting more attention and global competition increases, differentiation will become essential for the success of your injectable drug. Customize your parenteral drug delivery solutions with us, meeting your specific requirements and supporting your brand image.

Aptar Pharma’s world-leading Rigid Needle Shield for biotech and GLP-1 applications.
Aptar Pharma’s world-leading Rigid Needle Shield for biotech and GLP-1 applications.

World Leading Rigid Needle Shield (RNS) Solutions

Accelerate your injectable GLP-1 product development with our world leading RNS solutions for ½” needles and specialized designs for auto-injectors. Customize your RNS to your specific requirements and GLP-1 drug delivery needs.

Secure your long-term supply of GLP-1 injector components with our new manufacturing lines, robotization and state-of-the-art processes that ensure reproducibility and quality.

Aptar Pharma’s PremiumCoat® ETFE film-coated PFS syringe plunger for GLP-1 and sensitive drug developments.

Platform of Syringe and Cartridge Plungers

Accelerate and derisk your GLP-1 drug development and injectable reformulation project with our platform of GLP-1 pre-filled syringe (PFS) plunger and cartridge plunger components that leverage our pure bromobutyl composition.

This rubber formulation is also used for our PremiumCoat ® line of ETFE film-coated plungers , that ensure the maximum protection of sensitive drug product. PremiumCoat ® ’s proprietary 3-rib design also helps to ensure optimal system performance and seamless integration with GLP-1 auto-injectors.

PremiumFill® range of pre-filled-syringe plungers and vial stoppers meeting Annex 1 contamination control requirements.

Advanced Parenteral Closure Solutions

Further derisk your injectables manufacturing and support your compliance with EU Annex 1 regulations by combining our GLP-1 compatible syringe plungers with our Advanced Parenteral Closure Solutions:

Expert drug development services for injectable drugs with E&L studies, particulate analysis and primary packaging validation

Drug Development Services

Trust the experts from Aptar Pharma to support your GLP-1 injectable drug development project and validate your choice of primary packaging. Gateway Analytical’s services help to derisk and accelerate your drug product development with:

Patient uses Noble’s autoinjector trainer to simulate a self-injection enhancing patient adherence.

Patient Services

Ensure the success of your injectable drug beyond the development stages and partner with Aptar Digital Health and Noble to optimize the therapeutic outcome for your GLP-1 patients. Our Human Factor studies, drug delivery training kits and digital health solutions enhance patient engagement and adherence, which are critical for the efficiency of chronic diabetes and obesity treatments.

Product Details

4900GS styrene butadiene
½’ design.

RNS for autoinjector

Customization

1 mL and 1-3 mL syringe plunger formats, PremiumCoat® ETFE film-coated and uncoated options.

3 mL cartridge plunger

Improved specification for key contamination criteria (particles, fibers, biological)

Pre-filled syringe and cartridge plungers are available RTU and packaged in poly-ethylene bags or Rapid Transfer Port (RTP) bags to minimize particulate contamination risks on filling lines.

Getinge (105mm, 190mm)
Sartorius (110mm).

Available in polyethylene (Ready-to-Use) or Tyvek (Ready-to-Sterilize) options

Contact Aptar Pharma’s Parenteral Expert Team Today

Learn more about how we can support your compliance with EMA GMP Annex 1 revisions and optimize your operations with our advanced injectable packaging solutions.

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