Bidose (BDS) System

Unidose/Bidose Systems


Aptar Pharma’s Bidose (BDS) device is a two-shot, robust, primeless, easy-to-use system offering one-handed actuation and precise nasal drug delivery.

Available for liquid formulations, our BDS is designed to enable the systemic delivery of drugs without the need for injection or administration by a healthcare professional.

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The Two-Shot Nasal Bidose System with Proven Performance

Proven technology: FDA approved and commercialized

Aptar Pharma is a global leader in nasal drug delivery devices and has the broadest range of proven ENT solutions in the world. We have decades of experience and scientific knowledge in ENT solutions, which enable us to deliver innovative and effective nasal solutions for both local and systemic therapies.

Our patented Bidose (BDS) Liquid system has been approved by the FDA and EMA for the treatment of depression, and there are promising projects in the pipeline for other indications.

To date, millions of our Bidose and Unidose systems have been sold worldwide and are used successfully by thousands of patients every day across a range of treatment scenarios, making Aptar Pharma’s Bidose system the device of choice for two-shot nasal treatments.

Delivers accurate two metered nasal doses – every time

Our Bidose (BDS) system is applicable for intranasal therapies where very precise amounts of active CNS drug formulation is required. They reliably and accurately deliver their full metered doses with reproducible spray performance.

Two shot nasal dosage is ideal in nasal vaccine administration, with one shot in each nostril. It’s also ideal for crisis treatments with the second dose option available as a back-up.

The Bidose has an integrated dose indicator to assure patients of the doses used and to indicate the remaining doses in the device.

The integrated dose indicator helps patients and doctors alike to measure dose compliance.

Intuitive and ready-to-use system

Bidose (BDS) is simple to use by patients, caregivers and HCPs, and is ready-to-use, with no priming or shaking required.

Additionally, the Bidose is a very intuitive system, so there is no special training needed, which is a big advantage in crisis situations.

Ideal device for your drug repurposing projects

Drug repurposing can help you extend the lifecycle of your brand, respond to unmet needs and offer more patient-friendly solutions.

Aptar Pharma has vast experience in repurposing existing drugs for nasal delivery, especially injectable drugs, making them simpler and more convenient to use. Some examples of this can be found in the Unidose (UDS) section.

Nasal administration of drugs offers fast onset of action and relief of symptoms. Drugs delivered nasally enter the brain directly via the nasal mucosa and bypass the blood-brain barrier.

Supported by world class analytical services

Our broad range of analytical, development and regulatory services can help accelerate and reduce the risk in your drug product development journey. We can offer full support from R&D to regulatory submission and post launch services.

Additionally, preclinical solutions are available for clinical studies.

Bidose (BDS) System Advantages

  • Crisis and Rescue Treatments
  • Targeted and Reliable Drug Delivery
  • One-Handed Actuation
  • Limits Available Doses
  • Proven Microbiological Integrity
  • Tamper Evident Feature
  • Customization and IP
  • Ergonomic Design

Proven device for crisis and rescue treatments

Our BDS system delivers a two-shot formulation quickly and easily, which is crucial in emergency situations. This intuitive, easy-to-use device makes administration by a patient, caregiver or 3rd party simple and fast.

The Bidose system is ideal for the treatment of chronic CNS conditions.

Robust and reliable device for accurate dose delivery

Our Bidose system delivers two precise doses, reliably, whenever needed.

Simplifies dose administration

Our Bidose nasal drug delivery device is simple to use and requires low actuation force. Patients, parents and caregivers find the one-handed actuation and ease-of-use very comforting, especially in stressful crisis drug administration.

Our Bidose system limits the amount of drug available

The BDS is appropriate for treatments where two single doses are needed, and keeps extra drug product away from patients and their entourage, which is especially important in the case of drugs with a narrow therapeutic index or can be potentially addictive.

Your drug is protected

Your drug is protected in the BDS system with guaranteed microbiological purity.

Tamper evident feature protects the drug product

The tamper evident feature indicates if the device has been used before or mishandled.

Customization offers you IP protection

Customized designs are possible, and we can also offer IP protection for your drug product.

Ergonomic design and style ensures ease-of-use and accuracy

Our patented design minimizes any possible discomfort to use. The design enables steady, one-handed actuation and reliable delivery of each dose.

Product Details

Our Bidose System Can Bring New Life to Old Drugs

Our Bidose system can be part of your Lifecycle management and drug repurposing initiatives, bringing new life to old drugs.

Check out our Knowledge Hub or speak to an Aptar Pharma expert to find out more.

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