Ophthalmic Squeeze Dispenser (OSD) Technology Platform

Eye Care Dropper


Aptar Pharma’s Ophthalmic Squeeze Dispenser is the leading device for preservative-free prescription and over-the-counter products. Featuring unrivaled microbiological safety and a proven track record with more than  300 market references worldwide, it is the only FDA-reviewed technology for multidose, preservative-free systems in eye care.

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Clearly the World’s Favorite

Multidose preservative-free system makes preservatives obsolete

Preservatives in eye-care formulations, such as Benzalkonium Chloride (BAC), can lead to side effects with chronic use. The Ophthalmic Squeeze Dispenser (OSD) is the leading preservative-free multidose eye dropper worldwide to address this challenge.

The Ophthalmic Squeeze Dispenser’s purely mechanical Tip-Seal technology eliminates the need for preservatives and additives such as silver ions or surface coating.

Proven unrivaled microbiological safety helps ensure patient safety

Aptar Pharma’s patented Tip-Seal technology has been qualified by the industry’s most challenging tests and has passed worst-case scenario simulations.

Aptar Pharma provides a comprehensive data package for the Ophthalmic Squeeze Dispenser reflecting the most recently updated guidelines in highly regulated markets.

The first and only FDA-reviewed, preservative-free multidose eye dropper

Aptar Pharma offers the first and only U.S. FDA-reviewed technology for multidose preservative-free systems in eye care. Our Ophthalmic Squeeze Dispenser has been accepted by regulatory authorities worldwide, including the U.S. FDA, BfArM and ANSM.

Most accepted technology platform worldwide

The Ophthalmic Squeeze Dispenser is the leading preservative-free multidose (PFMD) technology for both consumer product and prescription eye-care medications, with a proven track record of more than 300 market references worldwide and counting.

Ophthalmic Squeeze Dispenser Advantages

  • Unrivalled Safety
  • Preservative-Free System
  • Versatile Platform
  • Convenience
  • Product Stability
  • Easy Filling
  • Established CMO Network
  • Service Packages Available

Proven unrivaled microbiological safety

Our challenging quality test systems are widely accepted by regulatory authorities and help ensure patient and product safety.

Purely mechanical technology eliminates need for preservatives

The purely mechanical integrity approach of our patented Tip-Seal technology prevents backflow into the tip. A sterile filter membrane filters any incoming air when the system is ventilated. This technology eliminates the need for any additives to the formulation and packaging material.

OSD Technology Platform offers widest application range for preservative-free eye-care treatments

Our versatile technology platform offers easy customization solutions for the Ophthalmic Squeeze Dispenser, including color customization to fit branding needs.

A choice of product features makes our OSD system highly adaptable to specific formulation needs, including prescription medications and over-the-counter products.

Convenient and intuitive handling for patients and consumers

The OSD provides easy handling and intuitive application while requiring low actuation force for the squeeze bottle. The compact product format makes the OSD convenient for on-the-go usage.

Metal-free fluid pathway and inert packaging materials protect eye‑care formulations

Inert and safe packaging is particularly important for sensitive eye-care formulations. The OSD’s fluid pathway is metal-free, enabling it to avoid any oxidative reactions of the formulation with ferric metals.

To protect highly sensitive or reactive formulations, particularly inert plastic materials can be used for the container and the spray pin of the Tip-Seal.

Compatible with existing filling technologies

The Ophthalmic Squeeze Dispenser can be implemented on existing filling lines and requires no major refitting of production facilities. The OSD’s easy filling process helps to simplify your manufacturing processes.

Reliable supply chain meeting high-quality standards

Our established worldwide CMO network covers a wide range of services: industrial filling at low and high volume CMOs, regulatory approvals, CDMOs and licensing offers. In addition, our supply chain partners for OSD squeeze bottles, fulfill the high-quality standards demanded by Aptar Pharma.

Service packages available to support your product development

Gold standard analytical and development lab services and comprehensive data packages are available to support the development of your preservative-free eye-care product. Our experienced regulatory affairs team supports registration processes worldwide.

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The Solution is Right Before Your Eyes

Realize your next global eye-care opportunity with our Ophthalmic Squeeze Dispenser.

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