Webinars, Pharmaceutical

The Nasal Drug Delivery Journey: from Systemic to Nose-to-Brain?

Nasal drug delivery devices can play a role in meeting many unmet medical needs, and an area within drug delivery generating much attention is the possibility of treating CNS diseases by the so-called “nose-to-brain” route.

September 16, 2016 5:00 PM London / 12:00 PM New York 1 Hour
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Presented by Pierre Carlotti Dr. Julie D. Suman Gerallt Williams
16 Sep 2016

Nasal drug delivery devices can play a role in meeting many unmet medical needs, and an area within drug delivery generating much attention is the possibility of treating CNS diseases by the so-called “nose-to-brain” route.

Presented by Pierre Carlotti, VP Marketing Communication, Aptar Pharma, Dr Julie Suman, President, Next Breath, an Aptar Pharma company and Dr Gerallt Williams, Director Scientific Affairs, Aptar Pharma, this webinar explores the growing area of CNS therapy using nasal drug delivery.

By 2030, there will be 1 billion people over 65 years of age worldwide compared to 600 million currently, and healthcare must adjust to this changing demography. In addition, we are faced with multiple unmet medical needs and healthcare costs are rising globally. As a consequence several adaptations are necessary, including new therapeutic options, shortened in-patient hospital stays, increased outpatient care and more self-administration of drugs.

The Central Nervous System (CNS) drug market is of interest as it comprises several areas, some with high unmet medical needs, such as depression, schizophrenia, Alzheimer’s disease, Parkinson’s disease, migraine, insomnia, ADHD (Attention Deficiency Hyperactivity Disorder), anxiety disorders and bipolar disorder. In 2015, the drug market for CNS was valued at $143 billion.

Nasal drug delivery devices can play a role in meeting some of these unmet medical needs, and an area within drug delivery generating much attention is the possibility of treating CNS diseases by the so-called “nose-to-brain” route.

The presentation covers several subjects related to the CNS market from different perspectives. A detailed review of the advantages of nasal drug delivery in relation to the unmet needs in the CNS market is also presented. The options available and the comparative technical merits of nasal devices will be discussed and Aptar Pharma shares its know-how gained from more than 30 years of experience in this specialized drug delivery field. Finally, the speakers look to the future and explore how some of these CNS diseases could possibly be treated via the nose-to-brain pathway.

Presented By

Pierre Carlotti

VP, Strategic Marketing

Pierre is a member of Aptar Pharma’s Management Committee. He’s responsible for all aspects of marketing and communication, from marketing plans and innovation roadmaps to new business branding, technical and scientific partnerships, and, more recently, connected health programs, for the Prescription Division and, since 2013, the Injectables Division. Pierre has a postgraduate degree in Biology and is an ISCE-Paris Business School graduate. Prior to joining Aptar, Pierre worked at Sanofi and West Pharmaceutical Services.

Dr. Julie D. Suman

PhD, President, Next Breath, an Aptar Pharma Company

Julie holds a B.S. in Pharmacy from Duquesne University (1996) and a Ph.D. in Pharmaceutical Sciences from the University of Maryland, Baltimore (2002). She is a co-editor for Respiratory Drug Delivery Proceedings, an international symposium, and an Affiliate Assistant Professor in the Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University. Julie is a Past-Chair of the AAPS Inhalation Technology Focus Group. She is also a licensed Maryland pharmacist. Julie has published her research in peer-reviewed journals, has presented during podium sessions at international meetings such as the FDA Visiting Professor Lecture Series, and has been an invited speaker at ANVISA in Brazil. Dr. Suman’s doctoral research, which focused on the relationship between in vitro tests for nasal sprays and in vivo deposition, has been recognized for excellence by a research award presented at the International Society for Aerosols in Medicine, 2001.

Gerallt Williams

Director Scientific Affairs, Aptar Pharma

Dr Gerallt Williams is Director Scientific Affairs at Aptar Pharma. After obtaining his PhD from the University of Wales, UK in 1985, Gerallt has held various industrial positions at Monsanto Inc. (UK), Fisons Ltd (UK), Valois (France) and Inhale/Nektar Therapeutics (USA).

Gerallt is now in charge of Scientific Affairs for the Aptar Pharma Prescription division, Le Vaudreuil, France and is engaged in the development of new devices for nasal, inhaled and injectable drug products.

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