Publications, Pharmaceutical

Aptar Pharma reviews the importance of silicone levels on vial stoppers

When developing new injectable drugs, manufacturers must consider the importance of primary packaging to  ensure the drug is protected from the initial filling process to being administered to a patient. Silicone is added to every elastomeric closure component and is essential to ensure the products perform well on filling lines and in conjunction with the glass container. The PremiumCoat® platform of vial stoppers, pre-filled syringe plungers and services combine a state-of-the-art Bromobutyl formulation with a market proven ETFE film that help limit the transfer of extractables and leachables into the drug formulation.

In this article, Aptar Pharma uses inductively coupled plasma optical emission spectrometry (ICP-OES) to demonstrate that our proprietary manufacturing process optimizes the distribution of silicone oil on our PremiumCoat®. By limiting the quantity of silicone that comes in contact with the drug product, PremiumCoat® derisks the development of sensitive drugs.

 
For more information on ONdrugDelivery.

 

Download Publication on PremiumCoat Solutions: Helping Control Level Silicone Protect Sensitive Therapeutics
Author(s): Sébastien Cordier Vincent Holterboch Estelle Verger
16 May 2022

Learn more about PremiumCoat® Platform

Find Out More about PremiumCoat®

This Might Also Be of Your Interest

13 Oct 2023

Injectable Primary Packaging support compliance with Annex 1 Revision

Publications, Pharmaceutical, Brand Differentiation, Market Insights, Product Solutions

Read More
4 Oct 2023

Ensuring Container Integrity at Various Temperatures

Webinars, Pharmaceutical, Market Insights, Product Solutions

Read More
14 Sep 2023

Quality, Safety & Regulatory Compliance for Elastomeric Closures

Publications, Pharmaceutical, Innovation & Insights, Market Insights, Product Solutions

Read More
23 Jun 2023

Approaches to Extractables and Leachables in Parenteral Drugs

Webinars, Pharmaceutical, Market Insights, Product Solutions

Read More
1 2 3 4 11
Back To Top