Publications, Pharmaceutical

Exploring How the Functional Properties of the PremiumCoat® 1-3mL Plunger Facilitate its Implementation on Filling Lines & Enable the Delivery of Sensitive Vaccines & Biotech Drugs

Choosing appropriate packaging for a drug is essential since interactions between drug and container can compromise patient safety. This is especially true for biologics and vaccines. This article introduces Aptar Pharma’s PremiumCoat® platform focusing on its application in the manufacture of prefilled syringes. Prefilled syringes are prized for their ability to limit drug waste and for easy administration at the point of use, a factor that makes them useful for seasonal vaccination of the type that may prove necessary for the long-term management of COVID-19. The PremiumCoat® 1 – 3ml plunger format combines a pure bromobutyl formulation with proven ETFE film technology to minimize leachables. It is particularly useful for vaccines and large-volume biologics and facilitates vial-to-prefill projects. Experimental data illustrate key aspects of the system’s performance.

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Author(s): Sébastien Cordier Dr. Laure-Hélène Guillemot Audrey Chardonnet
Drug Development & Delivery
5 Oct 2021
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