Publications, Pharmaceutical

Comparison of Pulmonary Deposition for Single and Multidose Dry Powder Inhalers with Indacaterol and Glycopyrrolate

An inhaled combination of indacaterol maleate and glycopyrronium bromide is routinely prescribed for the management of chronic obstructive pulmonary disease.

This paper describes work to determine the suitability of using a multi-unit dose dry powder inhaler to deliver this formulation in place of the single unit dose device associated with current commercial products. The results of in vitro and in silico studies indicate no difference in aerodynamic distribution or regional deposition respectively, between the two devices. This suggests comparable pulmonary performance and potential for interchangeability. The multi-unit dry powder inhaler offers practical advantages, such as eliminating the need to handle capsules, and requires a reduced inspiratory flow for effective drug delivery, making it the more patient-friendly option.

Download Publication
25 Jun 2020

Learn more about Aptar Pharma Expertise
in Pulmonary Drug Delivery

Find Out More

This Might Also Be of Interest

10 May 2023

Navigating the Development for Orally Inhaled and Nasal Drug Products

Publications, Pharmaceutical, Market Insights, Product Solutions, Device Innovations

Read More
24 Apr 2023

Navigating pMDI Reformulation 2.0

Publications, Pharmaceutical, Device Innovations, Market Insights, Product Solutions, Sustainability

Read More
19 Apr 2023

Developing More Sustainable pMDIs: A Q&A on Motivation, Progress and Challenges

Publications, Pharmaceutical, Sustainability, Brand Differentiation, Market Insights, Product Solutions

Read More
13 Mar 2023

Moving Towards Greater Recyclability in Drug Delivery – Sustainable Solutions b...

Webinars, Pharmaceutical, Sustainability, Device Innovations, Brand Differentiation, Market Insights, Product Solutions

Read More
1 2 3 16
Back To Top