Diagnostic Stoppers

Vial Components


Aptar Pharma’s Diagnostic Stoppers ensure high chemical inertness and optimal protection for Diagnostic products. Designed specifically to meet your primary packaging requirements for your liquid or powder applications, they are part of Aptar Pharma’s portfolio of containment solutions.

Download our Diagnostic Stoppers and Injectables portfolio

The Safe Vial Closure Solution for Your Diagnostic Applications

Pure quality formulations

Selecting the right packaging system is important, especially for lyophilized drugs. Aptar Pharma’s proprietary elastomeric formulations for Diagnostic Stoppers are designed and manufactured to provide the highest level of quality and safety.

Thanks to our in-house expertise, we offer a variety of innovative rubber formulations providing excellent tightness and high chemical inertness, which is essential for your products.

Ensuring quality protection of your drug formulations

All our proposed elastomeric formulations are compliant with international standards, such as the USP, EP, JP and ISO 8871, and are certified “not made with natural rubber”, allowing us to be your go-to drug delivery partner for all your injectable challenges. Our teams of experts in our International Technical Center can support you in your developments including selection of designs and formulations for specific applications.

Trusted by the world’s leading pharmaceutical companies

Our Diagnostic Stoppers are used by all the major pharmaceutical companies worldwide who are specialized in Diagnostic and Interventional Medical Imaging. Our 50+ years of experience, scientific expertise and high quality standards provide customers with a wide range of trusted injectable component solutions as well as support services, including analytical testing, regulatory support and post launch support, for diagnostic products development success.

Diagnostic Stopper Advantages

  • Perfectly Designed for Diagnostic Products
  • Optimal Compatibility and Protection
  • Perfectly Designed for Lyophilization Processes
  • Optimal Protection of the Lyocake

Our Diagnostic Stoppers are appropriate for DIN vials

Aptar Pharma’s range of Diagnostic Stoppers are appropriate for a wide range of DIN vials and have been specifically designed to answer the demanding requirements for Diagnostic applications including the lyophilization process.

Our range of Diagnostic Stoppers are adapted for both powder and liquid applications.

Optimal compatibility and protection for Diagnostic applications

Our Diagnostic Stoppers offer good chemical inertness, low extractable profile, non-cytotoxicity and low permeability ensuring maximum drug compatibility and protection throughout product life.

State-of-the-art design and low temperature resistance

The freeze-drying process is a very specific one. Our Diagnostic Stoppers have been developed to meet the demanding requirements of the lyophilisation process: ease of pre-positioning of the stoppers on the vials, resistance to very low temperatures during the freezing phase, impermeability to facilitate the drying processes, specific shapes to allow smooth closing of the vials, avoiding pop-off issues, and spacers to reduce the risk of sticking to the upper shelf after closing of the vials.

Low permeability and low level of residual moisture

A product dried to less than 3% of residual moisture will absorb moisture when exposed to an environment with greater moisture than its own level. The stability could then be compromised. Our Diagnostic Stoppers for powder formulations have been developed to guarantee a very low level of moisture, therefore offering protection of the lyophilized product throughout its shelf life.

Product Details

See Why our Diagnostic Stoppers Provide Optimal Protection

Contact our Aptar Pharma team of experts and find out how our Diagnostic Stoppers provide optimal protection and safety for your diagnostic products.


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