Advanced Preservative Free

Aptar Pharma - Advanced Preservative Free

THE MULTIDOSE SYSTEM FOR THE APPLICATION OF PRESERVATIVE FREE SOLUTIONS VIA THE NASAL ROUTE

Nasal formulations intended for use over a long period of time are generally preserved. However, it has now been recognized that preservatives can have a negative impact on the ciliated tissue in the nasal cavity.

Application Fields for Advanced Preservative Free
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Product Data Sheet: APF


Health authorities have published risk statements concerning the widely used preservative benzalkonium chloride.
Aptar Pharma‘s Advanced Preservative Free (APF) system is based on tip-seal/filter technology and avoids any chemical additives to grant sterility of the container content.
It has become a market success with over 120 million units sold world wide.

Key features:
  • Metal free fluid path – a solution for oxidizing formulation
  • Vented preservative free system
  • Filter membrane filters the air flow and prevents the product from contamination
  • Tip seal technology prevents clogging
  • Qualified with challenging microbiological tests (TSIT and CVIT)
  • Possibility of 360° application
  • Pharma compliant materials